Scientists from the Université de Montréal and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to ...

We have synthesized a hybrid subtilisin the solubility of which can be regulated by photoirradiation through coupling with a photoresponsive copolymer that carries spiropyran groups in its side chains ...

This method uses polymer modifications to tune enzyme activity for increased solubility in non-native solvents. Tuning the miscibility of enzymes in non-native solvent environments has important ...

A consortium of scientists has discovered new non-histone targets for one enzyme previously believed to modify only histones -- the group of proteins that creates tightly bundled packages of DNA ...

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...

Sanofi has developed a simpler way to create site-specific antibody-to-mannose-6-phosphate (M6P) conjugates that eliminates the need for enzyme remodeling. This more straightforward method makes M6P ...

The enzyme ALKBH1 can remove molecular modifications from transfer RNA, causing a measurable effect on protein translation in the cell, new research demonstrates. The study sheds new light on how ...

Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...

Paracatalytic enzyme modifications result from the oxidation of enzyme-substrate carbanions by extrinsic oxidants. During the oxidation of enzyme-activated substrates, transiently reactive ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

Cellular RNAs are chemically modified by many RNA modification enzymes; however, often the functions of modifications remain unclear, such as for pseudouridine formation in the tRNA TΨC arm by the ...