CCNs are a family of extracellular matrix proteins that regulate diverse aspects of cellular functions, and are involved in inflammation and tissue repair. Deregulation of CCN proteins is associated ...

The matrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases that consist of more than 21 human MMPs and numerous homologues from other species. They can be divided into ...

Scientists at the University of Helsinki have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Extracellular ...

Conexeu Sciences Inc. (“Conexeu” or the “Company”), a biotechnology innovator redefining regenerative medicine through a next-generation ...

New images are providing the first visual evidence of a long-postulated physical link by which genes can receive mechanical cues from its microenvironment. Created by integrating six different imaging ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

Combining micropillar deflection analysis, atomic force microscopy, and immunofluorescence staining provides a method for ...

Animal models are widely used for evaluating a drug in its development stage, but tighter regulations on animal testing and limitations resulting from differences among species are driving the demand ...

In a recent study published in NPJ Microgravity, scientists explore the impact of spaceflight on human vascular smooth muscle cells at the transcriptomic level. Study: Spaceflight effects on human ...