Cells have an internal skeleton that maintains their structure and also drives their movement. Known as the cytoskeleton, ...

Recent evidence points to cell-cycle independent functions for cyclin, cyclin-dependent kinases (CDKs) and CDK inhibitors (CKIs). In particular, the involvement of these proteins in the regulation of ...

The actin cytoskeleton is a dynamic network made up of actin polymers and associated actin binding proteins. The actin cytoskeleton was originally isolated as a component of the actomyosin complex in ...

Dysfunctions and malformations in the scaffold of a cell are thought to contribute to heart muscle weakness, neurodegenerative disease and even deafness. Now biophysics research at The University of ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...